Materials include information on theological issues and include items examining the meaning of books and verses in the Bible. Materials also pertain to Christian anti-communist organizations, including Billy James Hargisís Christian Crusade Against Communism and Fred Schwarzís Christian Anti-Communism Crusade. Also included are files relating to various religious groups such as the Church of Christ, Catholics, Jehovahís Witnesses, Lutherans, Seventh Day Adventists, and others. Materials include religious newspapers and pamphlets. Other items pertain to social issues from a conservative Christian perspective, including marriage and divorce, sex, and abortion.

The series may include topical correspondence and Bales writings. Other related materials may be found in Series II, Series III, and the Bales Library collection. For information on evolution, see Series VI. For information on Mormonism, see Series IX.